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Laboratories & Cleanroom

ORB Group > Laboratories & Cleanroom

State of art laboratories

The ORB Incubator offers access to a wide range of cutting-edge scientific equipment through its state of art laboratories and cleanroom. The ORB offers training to internal and external users. Clients are able to book the laboratories or receive services offered by ORB at these laboratories.

ORB Incubator scientific and processing facilities including:

Pharmaceutical testing
Patch Clamping Facility
Cell Culture Facility
Electronics Facility
Spectroscopy Facility
Semiconductor Facility
Design Facility

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Training

 

ORB provides training courses and certificates for different techniques

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Equipment

 

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Consultation

 

ORB research intelligence solutions answer most challenges

ORB's team are experts in modelling, design, fabrication and characterisation on the nano-scale alongside software development.

Spectroscopy Facility

The spectroscopy facility at ORB Incubator provides high resolution, state-of-the-art light and electron microscopy technologies for imaging and analysing the molecular and structural organisation of cells, tissue bioengineered materials and other materials. The spectroscopy core facility will provide strong technical support for multi-disciplinary research and industries. The facility sites are open to all members of the ORB community as well as to external academic and industry researchers. We will also provide services, teaching and training for university research communities.

Technologies offered:

  • FEI Krios/Titan TEM
  • FEI Q250 SEM
  • FEI Helios NanoLab 1200AT DualBeam
  • FEI SEM/FIB dual beam system
  • Nicolet™ iS™ 50 FT-IR Spectrometer
  • PicoSpin™ 80 Series II NMR Spectrometer
  • Olympus IX71 inverted phase/fluorescence
  • K-Alpha™+ X-ray Photoelectron Spectrometer (XPS)
  • PHI Nano TOF II
  • inVia™ Qontor® confocal Raman microscope
  • Veeco Dimension 3100 AFM

Cell Culturing Facility

The Cell Culture Facility at ORB provides reagents, equipment, technical expertise, consultation and training to support mammalian and insect cell culture efforts. The facility covers wide range of services including basic cell culture support, cell propagation, generation of culture supernatants, hybridoma production to generate monoclonal antibodies, development of gene-manipulated mouse embryonic stem cells, establishment of primary cultures from human and animal tissue samples, cell transformation, cell banking and screening for detection of mycoplasma contamination in cultured cells, consulting to assist in experimental design and use of sterile workstations for investigators without their own facilities.

Technologies offered:

  • Incubator
  • Cell Counter
  • Inverted Microscope
  • Liquid Nitrogen (N2) freezer
  • Steriliser (autoclave)
  • pH meter
  • Osmolarity measuring device
  • Refrigerator and freezer (–20°C to–80°C) and Water Purification
  • Cell Culture Laminar Flow Hood and Water Bath

Pharma Testing Facility

ORB Incubator's Pharmaceutical Facility provides independent, contract analytical services to the ORB's network and global pharmaceutical and related industries. The facility provides Quality Control Testing, Method Development, Validation, Stability Storage and Testing of pharmaceutical raw materials and finished products. At this facility we build partnerships with our customers, who not only recognise our expertise in analytical chemistry and standards of service but also value our integrity and impartiality. MHRA and FDA approval ensure that the service is at the very highest level for cGMP analysis.

Technologies offered:

  • J57TPN Automatic Refractometer
  • Easy Clean Sampling System (ECS)
  • Refracto 30GS Extended RI Measuring Refractometer
  • J57WR Bench Automatic Refractometer for Chemical QA
  • Rotary Micro Riffler Sample Splitter from Quantachrome
  • PFT Powder Flow Tester from AMETEK Brookfield
  • ZT 720 Series Automated Disintegration tester from STEQ America
  • LabEye Digital Video System
  • ezfill 4500 Dissolution Media Preparation from Distek, Inc.
  • Evolution 4300 Programmable Syringe Pump Dissolution
  • VIP 4400 Dissolution Vessel Washer from Distek, Inc.
  • MultiCheck 6 STEQ America
  • Evolution 4300 Programmable Syringe Pump Dissolution
  • FreeZone -105°C 4.5 Liter Cascade Benchtop Freeze Dry System
  • Krüss Contact Angle (DSA10)
  • Hemo Degradation Rate Tester

Patch Clamping Facility

The patch clamp facility at ORB Incubator is equipped with state of the art patch-clamp technology. Our setups are equipped with systems for rapid drug application. The facility allows whole-cell recordings or single-channel analysis in various expression systems that can be conducted to test the effects of drugs on voltage-gated or ligand-gated ion channels. Although full human plasma or other relevant proteins application schemes and assay conditions can be adapted for needs inside this facility.

Technologies offered:

  • Inverted confocal microscope
  • Anti-vibration table
  • Manipulator
  • Micropipette puller
  • Digitizer and Amplifier and pClamp
  • High speed pressure clamp
  • Aspiration pump (peristaltic or vacuum)
  • Vacuum machine
  • Alicona Mex software
  • Microforge (MF-900 Narishige) & MPS
  • Digital Manometer
  • Computer and screens
  • Piezo electric actuators
  • XYZ high precision stages
  • Pressurised air cylinder
  • Faraday cage
  • Perfusion system

Electronics Facility

The Electronics Facility provides design and characterisation services on the ORB Incubator site. Capabilities include analog, digital, and RF design as well as signal processing and software development. In addition, the facility provides circuit simulation, mathematical modelling, and mechanical design in support of prototype production and construction of circuits and instrumentation.

Technologies offered:

  • Cyclic Voltammetry
  • Impedance Specroscopy
  • Hall-Effect
  • Spectrum Analyzers
  • Signal Analyzers
  • Network Analyzer
  • LCR Meter
  • Multimeter
  • Kulicke & Soffa 4127 Wirebonder
  • ION 100 Gas Plasma Cleaning System
  • Oscilloscope
  • Keithley 4200 IV Measurement Unit

Semiconductor/Design Facility

Semiconductor / Design facility is engaged in Research & Development in the area of microelectronics / nanoelectronics and 2D/3D design and prototyping to meet the strategic needs of the ORB Incubator and external industries. The facility has integrated facilities / supporting infrastructure all under one roof and undertakes activities focused on Design, Development, Fabrication, Assembly & Packaging, Testing and Quality Assurance of CMOS, MEMS, Hi-Rel Boards, Radio Sonde Systems and electronic sub systems for various applications.

Technologies offered:

  • FEI flexProber System for Semiconductors
  • PEO-604 Semiconductor Furnace
  • Raith 150-TWO Electron Beam Lithography
  • Semi Automatic Wafer Probers Semiprobe
  • STS Multiplex PECVD
  • Stratasys Objet260 Connex3 3D Printer
  • PicoQuant Laser Cutting
  • TCAD
  • GrabCAD Voxel

Cleanroom

The MSSL ISO class 5 cleanroom facility at ORB is based upon the horizontal laminar flow design, with one complete end wall being a bank of HEPA (High Efficiency Particle Air) filters. Typical activities taking place within the cleanroom facility are: Assembly, test and integration of space flight hardware components, instruments and structures and optical components and structures.

Equipment:

  • ESCO Versati™ Micro Centrifuge
  • ESCP Frontier® Acid Digestion™ Fume Hood
  • ESCO Streamline® Compounding Aseptic Containment Isolator Fume Hood
  • ESCO Ventilated Balance Enclosure
  • ESCO NordicSafe® Biological Safety Cabinets
  • ESCO Cleanroom Air Showers
  • ESCO Garment Storage Cabinet
  • Qsonica Q800R2 Sonicator
  • IKA Magic Lap Dispenser
  • Microsphere Production Unit
  • Hotplate
  • Spinner
  • Mask Aligner
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